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            當前位置: 首頁> 產品中心> 免疫學 > 免疫細胞組織化學分析 > Vector Labs Fluorescein labeled Lycopersicon Esculentum (Tomato) Lectin (LEL, TL)
            Vector Labs Fluorescein labeled Lycopersicon Esculentum (Tomato) Lectin (LEL, TL)
            目錄號 FL-1171 售價 2576.00元
            規格 1mg 運輸溫度 冰袋
            其他名稱 Lycopersicon esculentum agglutinin(LEA),FITC Conjugate; Fluorescein labeled Lycopersicon Esculentum 保存溫度 2-8℃避光保存
            CAS號 N/A 有效期 1年
            應用 血管功能研究(內皮細胞標志物) 訂購數量
            產品簡介:

            Fluorescein labeled Lycopersicon Esculentum (Tomato) Lectin (LEL, TL)

            綠色熒光標記番茄凝集素



            產品標簽

            番茄凝集素(Tomato lectin);FITC-LEL;Intravascular perfusion血管內灌注;Lectin perfusion 凝集素灌注;Microvasculature 微血管;Endothelial cells 內皮細胞;


            產品信息【原裝正品,現貨供應,大量引用文獻支持】

            產品名稱

            產品編號   

            規格         

            目錄價(元)

            Fluorescein labeled Lycopersicon Esculentum (Tomato) Lectin (LEL, TL) 

            FL-1171

            1mg

             2576

            【溫馨提示】:見我司(懋康生物)整理的Vector Labs血管功能研究-番茄凝集素產品專題。


            產品描述

            番茄凝集素(Tomato lectin,Lycopersicon Esculentum Lectin(LEL)),是一種非常穩定的單亞基糖蛋白,約含有等量的蛋白質和碳水化合物。據報道其糖類部分由85%阿拉伯糖和15%半乳糖組成,在溶液中可能形成多聚體聚合物。番茄凝集素雖然和土豆凝集素、曼陀羅凝集素(DSL)和麥胚凝集素(WGA)有部分相同的特異性,但在許多多面呈現出獨特之處。番茄凝集素LEL能夠很好地與血型糖蛋白(glycophorin)和Tamm-Horsfall糖蛋白結合,能夠有效結合和標記嚙齒類動物的血管內皮(vascular endothelium)。


            本品為綠色熒光素標記的番茄凝集素(來源于Lycopersicon esculentum),Ex/Em=495/515nm,通過血管內灌注法或直接染色組織切片能快速且有效的檢測和可視化嚙齒類動物的血管和小膠質細胞。


            產品特征

            Synonyms

            Lycopersicon esculentum agglutinin(LEA),FITC Conjugate;

            Fluorescein labeled Lycopersicon Esculentum (Tomato) Lectin; FITC-LEL; FITC-LEA;

            Sugar Specificity

            [GlcNAc]1-3, N-Acetylglucosamine

            Applications

            Immunofluorescence, Glycobiology

            Conjugate

            Fluorescein(Ex/Em=495/515nm)

            F/P molar

            2

            Concentration

            2mg/ml

            Solution

            10 mM HEPES, 0.15 M NaCl, pH 7.5, 0.08% sodium azide, 0.1 mM Ca++, 5mg/ml β cyclodextrin

            Free Fluorescein

            None

            Storage

            2-8℃ in the dark


            相關產品:

            產品名稱

            產品編號        

            規格              

            目錄價(元) 

            Fluorescein labeled Lycopersicon Esculentum (Tomato) Lectin   (Ex/Em=495/515nm,綠色熒光)

            FL-1171

            1mg

            2300

            Texas Red labeled Lycopersicon Esculentum (Tomato)  Lectin (Ex/Em=595/615nm,紅色熒光)

            TL-1176

            1mg

            2360

            DyLight 488 labeled Lycopersicon Esculentum (Tomato) Lectin

            ( Ex/Em=493/518nm,綠色熒光)

            DL-1174

            1mg

            2220

            DyLight 594 labeled Lycopersicon Esculentum (Tomato) Lectin(Ex/Em=593/618nm,紅色熒光)

            DL-1177

            1mg

            2220

            Biotin labeled Lycopersicon Esculentum (Tomato) Lectin

            B-1175

            1mg

            1740

            Unconjugated Lycopersicon Esculentum (Tomato) Lectin

            L-1170

            2mg

            2280

            Agarose bound Lycopersicon Esculentum (Tomato) Lectin

            AL-1173

            2mg

            3660


            引用文獻【Vector Labs】

            Huang J et al. Regression of established tumors and metastases by potent vascular endothelial growth factor blockade. Proc Natl Acad Sci U S A. 2003 Jun 24;100(13):7785-90. PMID: 12805568【Vascular lectin perfusion, 100 μg in 100 μl of saline, fluorescein- labeled Lycopersicon esculentum lectin, Vector Lab】

            Inai T et al. Inhibition of vascular endothelial growth factor (VEGF) signaling in cancer causes loss of endothelial fenestrations, regression of tumor vessels, and appearance of basement membrane ghosts. Am J Pathol. 2004 Jul;165(1):35-52. PMID: 15215160【Vascular lectin perfusion, 100 μg in 100 μl of 0.9% NaCl, fluorescein- labeled Lycopersicon esculentum lectin, Vector Lab】

            Thurston, G., et al., Cationic liposomes target angiogenic endothelial cells in tumors and chronic inflammation in mice. J. Clin Invest, 1998. 101 (7): p. 1401-1413. PMID: 9525983

            Hashizume, H., et al., Openings between defective endothelial cells explain tumor vessel leakiness. Amer J Pathol, 2000. 156(4): p. 1363-1380. PMID: 10751361.【Vascular perfusion, biotin- or fluorescein isothiocyanate (FITC)-labeled Lycopersicon esculentum lectin, 100 μg in 100 μl 0.9% NaCl, Vector Laboratories】   

            Debbage, P.L., et al., Intravital lectin perfusion analysis of vascular permeability in human micro- and macro- blood vessels. Histochemistry Cell Biol, 2001. 116(4): p. 349-359.   

            Lee, J.C., et al., Interleukin-12 inhibits angiogenesis and growth of transplanted but not in situ mouse mammary tumor virus-induced mammary carcinomas. Cancer Res, 2002. 62(3): p. 747-755.   

            Akerman, M.E., et al., Nanocrystal targeting in vivo. Proc Nat Acad Sci Usa, 2002. 99(20): p. 12617-12621.   

            Gee, M.S., et al., Tumor vessel development and maturation impose limits on the effectiveness of anti-vascular therapy. Amer J Pathol, 2003. 162(1): p. 183-193.   

            Jilani, S.M., et al., Selective binding of lectins to embryonic chicken vasculature. J Histochem Cytochem, 2003. 51(5): p. 597-604.   

            Krasnici, S., et al., Effect of the surface charge of liposomes on their uptake by angiogenic tumor vessels. Int J Cancer, 2003. 105(4): p. 561-567.

             

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